New test quickly identifies patients whose postoperative pain can be effectively treated by hypnosis (IMAGE)
Caption
A: Giant magnetoresistive (GMR) biosensor array in its reusable cartridge. The black boxed area indicates the region magnified and displayed in B. The red line is inserted for scale. The GMR biosensor is 5 mm in length. B: A zoomed-in image of the GMR biosensor array overlaid with the pattern of functionalized probes on the surface of the individual sensors. The chip hosts an array of 80 individually addressable GMR biosensors, which can be seen in the image as red squares, some of which are covered by the overlaid pattern of probes. Each sensor can be individually functionalized with capture probes and is addressed and measured during readouts for sensor-specific changes in resistance due to the GMR effect. In the pattern used in this study, each single nucleotide polymorphism has both a wild-type (WT) and mutant-type (MT) probe set, as indicated by the matching colors above (dark for WT and light for MT), as well as positive and negative control probes. Six GMR biosensors are dedicated to each probe, for a total of six real-time measurements per probe type.
Credit
Dana L. Cortade and Shan X. Wang
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