Vaccines in comparison (IMAGE)

Max Delbrück Center for Molecular Medicine in the Helmholtz Association

Vaccines in comparison

Caption

After double vaccination with the live attenuated vaccine (A), the nasal mucosa in the hamster model is very well protected and shows hardly any changes from SARS-CoV-2 (B). The combination of live and mRNA vaccines (C) is also very effective, but the virus still finds small sites to attack (stained brown) in the nasal mucosa (D). In comparison, double intramuscular vaccines perform much worse in terms of protecting the nasal mucosa (E+F and G+H). They allow the virus to damage the upper tissue layers.

Credit

Anne Voß, Institute of Veterinary Pathology, Freie Universität Berlin

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