Figure 1 (IMAGE)
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Role of PV neuron activity in the awake and anesthetized brain. When the inhibitory PV neuron is activated in the awake brain, excitatory neurons are inhibited and vasoconstriction is observed (left). In the anesthetized brain, substance P is secreted by the PV neurons, which activates nNOS neurons and causes slow vasodilation (right). Optical imaging was used to measure HbT (total hemoglobin), which is used to infer the level of blood flow.
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Institute for Basic Science
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