Schematic of the procedure to map carnitine distribution. (IMAGE)
Caption
Mice muscles treated with d3-carnitine (deuterated) undergo electrically stimulated contraction for 60 minutes. Muscles are then cryosectioned and the distribution of d3-carnitine is mapped using a mass spectrometry technique. They found that contracted muscle cells showed elevated levels of d3-carnitine and d3-acetyl carnitine.
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Tokyo Metropolitan University
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