Promotor dominance (IMAGE)

Max Planck Institute of Immunobiology and Epigenetics

Promotor dominance

Caption

Example of a gene that contains two possible start sites (TSS), and two possible end sites (TES). Black boxes in the gene model show sequences that will be translated into protein. With conventional short-read mRNA sequencing, in which signal represents the accumulation of reads, it is not possible to distinguish different molecules. In long-read sequencing, each horizontal line represents one mRNA molecule from beginning to end. For the gene stathmin, we can see that TSS1 predetermines ending at TES1, and TSS2 will lead to TES2.

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MPI of Immunobiology & Epigenetics, Hilgers

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