First drug treatment for aneurysm in a mouse model (IMAGE)

RIKEN

First drug treatment for aneurysm in a mouse model

Caption

A mouse model of intracranial aneurysm and successful drug treatment. (Left) A photo of normal basil artery in the mouse brain above and cross section below. (Middle) An aneurysmal basil artery that has ballooned to twice the diameter. The aneurysm was created in this specific artery by injecting a virus nearby that carried the discovered mutant PDGFRB gene. (Right) Treatment with the drug sunitinib blocks the abnormal activity of the mutant gene, and thus is able to prevent the aneurysm.

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RIKEN

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