Tangled tubules (IMAGE) Picower Institute at MIT Caption A figure from the paper shows microtubules becoming misdirected and tangled during late-stage development of a fly larvae lacking Perlecan. Credit Littleton Lab/MIT Picower Institute Usage Restrictions with credit License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.