The genetic and epigenetic structure of the four ethnic populations, and the correlation of the two structures. (IMAGE)

Science China Press

The genetic and epigenetic structure of the four ethnic populations, and the correlation of the two structures.

Caption

(A) The genetic structure of the population based on population SNPs. (B) The epigenetic structure of the population based on ethnic-specific DNA methylation sites. (C) The distribution curve of correlation values estimated between overall genetic distances and CpG methylation Manhattan distances of CpGs sorted with the values of Pst, the parameter to estimate phenotypic differentiation between populations. (D-E) The correlation curves based on the between-ethnic (D) or within-ethnic (E) comparison of genetic distances with CpG methylation Manhattan distances.

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