(IMAGE)

Tokyo Medical and Dental University

Caption

A. Overview of the parathyroid gland production method in this study. B. Fluorescent images of mouse ESC-derived PTGs generated in PTG-deficient mouse by single-step blastocyst complementation. Left: tdTomato, middle: antibody staining for Parathyroid hormone, right: merged image. C. Transplantation experiment of mESC-derived PTGs into mice modeling post-surgical hypoparathyroidism. The plasma ionized [Ca] (left graph) and the plasma stimulated PTH 1-84 (right graph) were recovered in mice transplanted with the produced PTGs.

Credit

Stem Cell Therapy Laboratory, TMDU

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.