Scheme of the mechanism of nickel-cobalt alloy nanocrystals inhibiting inflammasome activation. (IMAGE)
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Multiple stimuli trigger the activation of three inflammasomes: NLRP3, NLRC4, and AIM2. NiCo NCs suppressed the inflammasome assembly process by downregulating the long non-coding RNA Neat1, thereby inhibiting the activation of three inflammasomes.
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