Figure 1 (IMAGE)

The Korea Advanced Institute of Science and Technology (KAIST)

Figure 1

Caption

Figure 1. Results of screening for compounds that increase astrocyte phagocytosis (A) Discovered that synthetic glucocorticoid (stress hormone) increases the phagocytosis of astrocytes through screening of FDA-approved clinical compounds. (B-C) When treated with stress hormones, the phagocytosis of astrocytes is greatly increased, but this phenomenon is strongly suppressed by the GR antagonist (Mifepristone). CORT: corticosterone (stress hormone), Eplerenone: mineralocorticoid receptor (MR) antagonist, Mifepristone: glucocorticoid receptor (GR) antagonist

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KAIST Gliabiology Lab

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