TET2 gene deficiency fuels development of acute myeloid leukemia (IMAGE)

City of Hope

TET2 gene deficiency fuels development of acute myeloid leukemia

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The return (i.e., homing) of leukemia stem cells (green) to the bone marrow microenvironment/niche (red) is substantially enhanced by low levels of TET2, at right, compared to the wild-type version of the gene.

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Jianjun Chen Laboratory/City of Hope

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