Researchers have discovered a potentially safer yet effective treatment for multiple disorders that display altered dopamine signaling. The “key?” A molecule that targets a specific protein called the kappa opioid receptor (KOR). Researchers have discovered a potentially safer yet effective treatment for multiple disorders that display altered dopamine signaling. The “key?” A molecule that targets a specific protein called the kappa opioid receptor (KOR).

Mass General Brigham researchers compared their long-standing diagnostic decision support systems AI tool, DXplain, with modern large language models like ChatGPT and Gemini, finding DXplain performed slightly better. They say their findings, published in JAMA Network Open, suggest that combining DXplain with LLMs could enhance clinical diagnosis and improve both technologies.

A lab-designed molecule developed and extensively studied by scientists with Virginia Tech’s Fralin Biomedical Research Institute at VTC could represent a breakthrough in slowing tumor recurrence in glioblastoma, an aggressive and deadly form of brain cancer.