An analysis of 173,303 genomes from Pakistan is upending our understanding of human genetics, shaping development of new therapies and illuminating why drugs first tested in mice often fail in people.

Researchers demonstrated a new method of using decellularized cartilage with patient-specific cells to help enlarge the pediatric airways narrowed as a result of severe subglottic stenosis. The team demonstrated that this new method was faster, more effective and able to overcome issues associated with the current standard grafts such as donor site morbidity, insufficient tissue volume and delayed timeline.

Researchers demonstrated a new method of using decellularized cartilage with patient-specific cells to help enlarge the pediatric airways narrowed as a result of severe subglottic stenosis. The team demonstrated that this new method was faster, more effective and able to overcome issues associated with the current standard grafts such as donor site morbidity, insufficient tissue volume and delayed timeline.