Controlling cancer cells’ gluttony for glutamine
Peer-Reviewed Publication
Updates every hour. Last Updated: 30-Apr-2025 08:08 ET (30-Apr-2025 12:08 GMT/UTC)
Stem cell transplantation is used to treat several types of blood cancers, but carries the risk of a life-threatening side effect called graft-versus-host disease. Results from a clinical trial conducted by researchers at WashU Medicine showed adding the investigational drug itacitinib to standard care for "half-matched" stem cell transplantation may reduce rates of the disease, in which the donor’s stem cells attack the patient’s healthy tissues.
Researchers at the NYU Pain Research Center have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does not signal on its own, according to a study published in the Journal of Clinical Investigation. The findings hold promise for finding new treatments for arthritis and other forms of inflammatory and cancer pain, without the side effects that led recent therapies to fail in clinical trials.
First-of-its-kind sensor monitors fluctuating proteins within the body in real time. In an animal study, device accurately tracked biomarkers of inflammation. Device also could track protein markers for other illnesses, including heart failure.