A newly developed algorithm shows how a gene is expressed at microscopic resolution
Peer-Reviewed Publication
Updates every hour. Last Updated: 25-Apr-2025 04:14 ET (25-Apr-2025 08:14 GMT/UTC)
A long-standing goal of neuroscience is to understand how molecules and cellular structures on a microscale give rise to communication between brain regions at the macroscale. A study published in Nature Neuroscience now identifies, for the first time, hundreds of brain proteins that explain inter-individual differences in functional connectivity and structural covariation in the human brain.
Ryan K. McBain, ScD, a health economist in the Center for Integration Science in Global Health Equity at Brigham and Women’s Hospital, is the lead author of a paper published in The Lancet, “Effectiveness, cost-effectiveness, and positive externalities of integrated chronic care for adults with major depressive disorder in Malawi: a stepped-wedge cluster-randomised trial.”
In lower-income countries, common mental disorders account for more years lived in disability than HIV and malaria combined, yet most of those affected never receive treatment because of the cost. A new study finds that treating people in low-income countries for major depressive disorder can also help improve their physical health and household members’ wellbeing, demonstrating that mental health treatments can be cost effective.