VCAM1-APOE信號通路可作為阿爾茲海默症的潛在治療靶點 (IMAGE) Hong Kong University of Science and Technology Caption 該圖闡明了VCAM1-APOE信號通路可作為阿爾茲海默症的潛在治療靶點。白介素33(IL-33)增加小膠質細胞中VCAM1的表達 (2),誘導小膠質細胞向與APOE相結合的澱粉樣蛋白(Aβ)沉積遷移 (3),從而促進小膠質細胞對大腦中Aβ斑塊的清除 (4)。 Credit 香港科技大學 Usage Restrictions None License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.