Figure 3. Relationship between volume of reactive astrogliosis and prognosis in patients with glioblastoma and cancer stem cells (IMAGE)

Institute for Basic Science

Figure 3. Relationship between volume of reactive astrogliosis and prognosis in patients with glioblastoma and cancer stem cells

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A. Immunofluorescence images showing GFAP, Ki-67, and CD133 in the peri-tumoral region of glioblastoma patients.

B. The proportion of GFAP+ and/or CD133+ in Ki-67+ cells in glioblastoma patients.

C. The 11C-acetate uptake area beyond the contrast-enhanced MRI was defined as VolumeACE-MRI.

D. Kaplan–Meier Survival analysis showed significant differences in progression-free survival (PFS) between the two groups with a VolumeACE-MRI cutoff value of > 5.06cc.

E. Kaplan–Meier Survival analysis also showed significant differences in overall survival (OS) between the two groups with a VolumeACE-MRI cutoff value of > 5.06cc.

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Institute for Basic Science

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