Estimates of overall survival (IMAGE)
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The study revealed significant overall survival (OS) benefits with the combination of pyrotinib and fulvestrant for HR+/HER2+ metastatic breast cancer patients. Notably, trastuzumab-resistant patients achieved an exceptional 3-year survival rate of 95.8% (95% CI: 88.2–100%). Furthermore, patients receiving prior endocrine therapy had a 3-year survival rate of 89.8%, highlighting the potential of this combination therapy in extending survival for specific patient subgroups.
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Ying Wang
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