fig 3 (IMAGE)

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fig 3

Caption

The role of USPs in PCD in BC. This figure summarizes the mechanisms of USPs in PCD-related proteins or pathways in BC, which were discussed in this review article. (Note: USP: ubiquitin specific protease; ATG14L: autophagy-related gene 14-like protein; NLRP3: innate immune receptor protein (NOD-, LRR- and pyrin domain-containing 3); GSDME: gasdermin E; IGF2BP1: insulin Like growth factor 2 mRNA binding protein 1; ECT2: epithelial cell transforming factor2; CPT1A: carnitine Palmitoyltransferase 1A; SQSTM1: sequestosome 1; m6A: N6-Methyladenosine; mTOR: mechanistic target of rapamycin; KPNA2: karyopherin alpha2; ATG5: autophagy-related gene 5; Trf1: transferrin receptor 1).

Image link https://ars.els-cdn.com/content/image/1-s2.0-S2352304224001387-gr3_lrg.jpg      

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Genes & Diseases

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