The protein level of NR2F1 is increased in the ASC model. (IMAGE)
Caption
(A) The anesthetized and dilated mice were positioned beneath a microscope for the ASC modeling procedure. (B) Cataract lesions in control and ASC mice using a slit lamp. (C) Hematoxylin and eosin staining in lens section of control and ASC mice. Scale bar, 100 μm. (D) Masson staining of the two groups. Scale bar, 100 μm. (E) The immunofluorescence results of FN1 and VIM in lens slides of control and ASC groups. Scale bar, 50 μm. (F, G) The protein expression and quantification of apoptosis-related markers BAX and CASP3 in control and ASC groups. n = 3 per group; mean ± standard deviation; **P < 0.01; unpaired student's t-test). (H, I) The protein level and quantitative chart of NR2F1 in the two groups mentioned above. n = 3 per group; mean ± standard deviation; *P < 0.05; unpaired student's t-test. NR2F1, nuclear receptor subfamily 2 group F member 1; ASC, anterior subcapsular cataract; FN1, fibronectin 1; VIM, vimentin; BAX, Bcl-2-associated X; CASP3, caspase 3.
Credit
Genes & Diseases
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