Effects of BMP9 on SIRT5 expression in mesenchymal stem cells. (IMAGE)

Compuscript Ltd

Effects of BMP9 on SIRT5 expression in mesenchymal stem cells.

Caption

(A) Real-time PCR analysis showed the effect of BMP9 on SIRT5 mRNA expression levels in MEFs. (B) Western blot assays showed the influence of BMP9 on SIRT5 protein levels in MEFs. (C) Quantitative analysis of Western blot data highlighted the impact of BMP9 on SIRT5 protein abundance in MEFs. (D) Real-time PCR results showed the endogenous SIRT5 mRNA expression patterns in various progenitor cell types. (E) Fluorescent and phase images showed the infection results of recombinant adenoviruses (a: AdBMP9, b: AdSIRT5, c: AdsiSIRT5), Western blot results showed the effects of recombinant adenoviruses on the protein level of targets (d: AdBMP9, e: AdSIRT5, f: AdsiSIRT5), and quantitative results of Western blot assay showed the effects of recombinant adenoviruses on the protein level of targets (g: AdBMP9, h: AdSIRT5, i: AdsiSIRT5). Scale bar = 200 μm ∗p < 0.05 and ∗∗p < 0.01 versus control. BMP9, bone morphogenetic protein 9; SIRT5, sirtuin 5; MEFs, mouse embryonic fibroblasts.

Credit

Genes & Diseases

Usage Restrictions

Credit must be given to the creator. Only noncommercial uses of the work are permitted. No derivatives or adaptations of the work are permitted.

License

CC BY-NC-ND

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.