Figure 2. Photoacoustic detection of NADH with LF-MP-PAM. (IMAGE)

Light Publishing Center, Changchun Institute of Optics, Fine Mechanics And Physics, CAS

Figure 2. Photoacoustic detection of NADH with LF-MP-PAM.

Caption

Figure 2.  Photoacoustic detection of NADH with LF-MP-PAM. (a) Photoacoustic signal of NAD(P)H detected from a phantom NADH standard embedded in gel, demonstrating the system's sensitivity. (b) Endogenous NAD(P)H signal recorded from both mouse brain slices and cerebral organoids, highlighting the capability of LF-MP-PAM to detect metabolic activity in biological tissues. (c) Deep-tissue imaging in cerebral organoids showing robust NADH detection in deeper layers with minimal signal loss, emphasizing the superior penetration depth and efficiency of LF-MP-PAM.

Credit

Tatsuya Osaki, W et al.

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CC BY

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