Formation of larger lipid compartments through fusion of lipid vesicles (IMAGE)

Swiss Nanoscience Institute, University of Basel

Formation of larger lipid compartments through fusion of lipid vesicles

Caption

Specific positively charged amino acids of the diphtheria toxin domain (gray dots) bind to negatively charged vesicle membranes (T-SVs - T-domain-associated smaller vesicles). The vesicles then adhere to a glass surface. This leads to asymmetric tension in the membrane (red). When other free-floating vesicles in the solution fuse with an adhering vesicle, the membrane tension is reduced and larger vesicles (LVs) are formed. 

Credit

P. Jasko, University of Basel and PSI

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