Fig. 2 (IMAGE)

The University of Osaka

Fig. 2

Caption

Sugar migration from blood to saliva and impact on oral health.

 (A) Schematic illustration of glandular saliva collection. (B) Principal component analysis of metabolomic profiles from blood as well as glandular, and whole saliva. Group differences were evaluated using (permutational multivariate analysis of variance (PERMANOVA), and the proportion of variance explained is indicated. (C) Associations between major monosaccharides and glycemic parameters. (D) Associations of blood–saliva glucose and fructose migration with oral health indicators. β coefficients were estimated using age- and sex-adjusted linear regression models.

Credit

2025, Akito Sakanaka et al., Diabetes alters the supragingival microbiome through plasma‑to‑saliva migration of glucose and fructose, Microbiome

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