Figure 3 (IMAGE)

Tohoku University

Figure 3

Caption

The brain energy paradox during REM sleep. During REM sleep, astrocytic pyruvate levels increased along with the increase in local brain blood volume (left). In contrast, when neuronal ATP was measured with a fluorescent sensor, neuronal ATP decreased despite the increase in local brain blood volume (right). These findings suggest that, during REM sleep, increased energy supply does not simply lead to increased neuronal ATP. Instead, energy flow appears to be dynamically reorganized among blood vessels, astrocytes, and neurons.

Credit

Yusuke Takahashi, Yoko Ikoma, Ko Matsui

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