Pathway enrichment analysis reveals coordinated disruption of amino acid and purine metabolism in BCD (IMAGE)
Caption
(a) Pathway enrichment bubble plot. Bubble size represents statistical significance, and the x-axis indicates enrichment strength (Rich Factor). Amino acid metabolism shows the highest enrichment (0.7), followed by purine metabolism (0.6). (b) Purine metabolism network with AMP serving as the central hub connecting multiple downstream metabolites. Node size reflects statistical significance, and the numbers indicate fold changes. (c) Amino acid interaction network showing complex metabolic interconnections. Node colors represent amino acid classes, whereas edge colors indicate reaction types. Glutamate and α-ketoglutarate emerge as central regulatory hubs.
Credit
Yingke Zhao
Usage Restrictions
Credit must be given to the creator. Only noncommercial uses of the work are permitted.
License
CC BY-NC