Neural Implant in Korea Remotely Controlled from the United States, Bringing Brain Research into the IoT Era (IMAGE)
Caption
Figure 3. Validation of wireless drug delivery and optogenetic stimulation in freely behaving rats. (Left) Confirmation of the optofluidic probe's implantation site in the nucleus accumbens (NAc) and verification of the drug diffusion range using Evans Blue dye. (Center) Dose-dependent changes in locomotor activity following wireless low- and high-dose cocaine infusion into the brain at 4 weeks post-implantation. (Right) Verification of the combined effect of drug delivery and optogenetic stimulation on neural circuit modulation through a conditioned place preference (CPP) test.
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