Figure1 (IMAGE)

Sungkyunkwan University External Affairs Division (PR team)

Figure1

Caption

Schematic illustration showing the PilQ secretin outer-membrane channel during type IV pilus assembly being blocked by SlkA or SlkB protein plugs. SlkA/B occupy the PilQ lumen before docking of the inner-membrane complex, thereby limiting the influx of external compounds.

Credit

Kwon, O.H., Lee, Y., Ryu, B. et al. Secretin-interacting plug proteins prevent antibiotic influx during type IV pilus assembly in Pseudomonas aeruginosa. Nat Commun 17, 7000 (2026). https://doi.org/10.1038/s41467-026-73864-w

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