Figure2 (IMAGE)

Sungkyunkwan University External Affairs Division (PR team)

Figure2

Caption

Three-dimensional structure of the protein plug complex within the outer-membrane channel determined by cryo-electron microscopy, compared with its organization inside bacterial cells. The Slk plug density observed in the purified protein complex closely aligns with the central density in the PilQ lumen observed during type IV pilus assembly in cells.

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Kwon, O.H., Lee, Y., Ryu, B. et al. Secretin-interacting plug proteins prevent antibiotic influx during type IV pilus assembly in Pseudomonas aeruginosa. Nat Commun 17, 7000 (2026). https://doi.org/10.1038/s41467-026-73864-w

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