The high-salt microenvironment promotes disease development in mice with DNCB/OVA-induced atopic dermatitis. (IMAGE)
Caption
(A) Schematic of the animal experiment procedure (B) Representative photos of dorsal skin in DNCB/OVA-induced atopic dermatitis in PBS- or NaCl-treated mice (C) Representative mouse model skin tissues are shown by hematoxylin–eosin staining (D) Time course of total skin lesion scores of PBS- or NaCl-treated mice (n = 5) (E) Scratching behavior examination (F) Quantitative reverse transcription PCR assay of the related target mRNA levels in the dorsal skin lesion. ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001 (G) Related target molecules secretion (ELISA) of the mouse model blood (n = 5). Statistical analysis was performed using Student's t-test. Data are expressed as mean ± standard deviation. ∗∗p < 0.01 and ∗∗∗p < 0.001.
Credit
Yingqiang Luo, Zhiqiang Song, Pengju Jiang, Lan Ge, Min Zhang, Zihao Zhou, Yaguang Wu, Jun Hu
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