Crowding increases enzyme activity (IMAGE)

Okinawa Institute of Science and Technology (OIST) Graduate University

Crowding increases enzyme activity

Caption

Crowding boosts enzyme activity. Simulations show the enzyme lactate dehydrogenase (LDH), surrounded by BSA proteins, can adopt an open or closed shape. In crowded conditions, the closed shape is favored, which allows the enzyme to carry out its reaction more easily, increasing its activity.

Credit

Dindo et al., 2026, 10.1038/s41467-026-77666-y

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License

CC BY

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