Dietary betaine supplements restore normal social interactions in mouse model of schizophrenia (VIDEO)
Caption
Mice with only one functional copy of the kif3b gene avoid social interactions, which researchers use as a behavioral indicator of schizophrenia. Mice with the same mutation raised on a diet supplemented with betaine show normal social behavior. Top left: Genetically normal mice raised on a standard diet interact with each other. Top right: Mutant mice raised on a standard diet avoid social interactions. Bottom right: Genetically normal mice raised on a diet supplemented with three times the normal amount of betaine have no changes to their social interactions. Bottom left: Mutant mice raised on a diet supplemented with three times the normal amount of betaine show normal social interactions.
Credit
Video by N. Hirokawa, CC BY, first published in Cell Reports DOI 10.1016/j.celrep.2021.108971
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Please include the following Creative Commons By Attribution credit: Video by N. Hirokawa, CC BY, first published in Cell Reports DOI 10.1016/j.celrep.2021.108971
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