Bipolar cells die off in the new type of retinal sheets (IMAGE)
Caption
a view of the retina after transplanting a retinal sheet grown from normal human stem cells (top) or the modified stem cells lacking the ISL1 gene (bottom). Bipolar cells are red. Looking at the bottom right image of each panel, we can see that the new type of retinal sheet lacks bipolar cells. This allows transplanted photoreceptors to connect better with host bipolar cells.
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RIKEN
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