MB, NGB, and CYGB blocked liver fibrosis in vivo (IMAGE)
Caption
Intravenously injected MB, NGB, and CYGB markedly suppressed liver inflammation, fibrosis and oxidative cell damage in fibrotic mice without adverse effects. Cont. untreated control; MB, NGB, CYGB: intravenous administration of MB, NGB, CYGB. H&E, hematoxylin and eosin staining; SiR-FG, Sirius red-fast green staining; SMA, stellate cell activation marker; CD68: macrophage marker; Neu-Dapi, Neutrofil marker – DAPI nuclear staining; 4-HNE, oxidative cell damage marker, 4-hydroxynonenal
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Osaka City University
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