Microscopic images of mouse ovarian cancers. (IMAGE)

University of Pittsburgh

Microscopic images of mouse ovarian cancers.

Caption

Microscopic images of mouse ovarian cancers treated with an immune checkpoint inhibitor drug. When cancer-associated mesenchymal stem cells are absent (left), immune cells (shown in red) are found throughout the tumor, but when cancer-associated mesenchymal stem cells are present (right), they create a barrier that traps immune cells at the border of the tumor.

Credit

Cascio et al., Sci. Adv. 7, eabi5790 (2021)

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License

CC BY-NC

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