Cartoon representation of severe hypoplastic left heart syndrome (HLHS). (IMAGE)

University of Pittsburgh

Cartoon representation of severe hypoplastic left heart syndrome (HLHS).

Caption

Cartoon representation of severe hypoplastic left heart syndrome (HLHS). A car with a faulty engine represents an HLHS heart with dysfunctional mitochondria. Sildenafil and tauroursodeoxycholic acid (TUDCA) are two potential drugs that could help rescue this dysfunction, acting like engine oil and coolant, respectively.

Credit

Courtesy of study authors

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For use with embargoed release.

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