A protein causes higher risk of severe cancer progression for men (IMAGE)
Caption
The schematic illustration shows the difference in TIMP1 levels between the sexes and the consequences in the course of the disease: Healthy males (left) exhibit a relatively low TIMP1 level. It increases sharply in cancer patients with a high risk of progression. Healthy female persons (right) have higher TIMP1 levels, which do not increase further in the case of cancer. The male-specific increase causes a significantly higher risk, both for metastasis of the tumor in the liver and for earlier death.
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© 2021 Hermann et al. Originally published in Journal of Experimental Medicine
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