Figure 3. Genetic correlation results of the multivariate GenLang GWAS analysis, with comparisons to those for the largest published GWAS of full-scale IQ in LDhub (IMAGE)

Max Planck Institute for Psycholinguistics

Figure 3. Genetic correlation results of the multivariate GenLang GWAS analysis, with comparisons to those for the largest published GWAS of full-scale IQ in LDhub

Caption

Summary statistics for full-scale IQ (n=257,828) were obtained from the Social Science Genetic Association Consortium. Genetic correlations between the multivariate GenLang results (blue-green), full-scale IQ (purple) and traits in LDhub reveal an overlap with cognitive traits, education, eyesight, chronotype, lifestyle, wellbeing, psychiatric disorders, pain, physical health and exercise, and socioeconomic status. A subset of representative traits is shown, out of 143 traits that showed significant associations with the multivariate GenLang results and 245 traits that showed significant correlations with full-scale IQ, of which 135 traits overlap, after correction for multiple testing for 535*2 traits (p<4.67 x 10-5). Significant correlations are shown in dark colours, non-significant correlations in light colours. Full results can be found in Dataset S13. Genetic correlation (rg) is presented as a dot and error bars indicate the standard error.

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Simon Fisher / Else Eising

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