Interactions of blood plasma protein fibrinogen with its neuronal receptors (IMAGE)

University of South Florida (USF Health)

Interactions of blood plasma protein fibrinogen with its neuronal receptors

Caption

Interactions of the blood plasma protein fibrinogen (Fg) with its receptors, cellular prion protein (PrPc) and intercellular adhesion molecule-1 (ICAM-1), on the surface of neurons are shown with red dots using a method called proximity ligation assay (PLA). The presence of red dots indicates interaction of the target protein with its receptor. Neuronal nuclei are shown in blue.

Credit

Microscopic images courtesy of David Lominadze Laboratory, USF Health

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