Aggregates of dysmorphic interneurons in TSC patient-derived brain organoids (IMAGE)

IMBA- Institute of Molecular Biotechnology of the Austrian Academy of Sciences

Aggregates of dysmorphic interneurons in TSC patient-derived brain organoids

Caption

Immunostaining for human interneuron marker (Secretagogin) identifies aggregates of dysmorphic interneurons in human cerebral organoids derived from TSC patients that are around 230 days old. Note that dysmorphic neurons show enlarged cell body and processes.

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©Knoblich/IMBA.

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