Kinesin-microtubule interactions (IMAGE)

Hokkaido University

Kinesin-microtubule interactions

Caption

Microtubule, a cytoskeletal filament, may function as a mechano-sensor to regulate intracellular transport by its motor protein, kinesin. Tension, flexure, or compression in the microtubule filament slowed down the kinesin movement along the microtubule due to increased intermolecular interaction, as proved by the molecular dynamics simulation (Syeda Rubaiya Nasrin, Christian Ganser, et al. Science Advances. October 13, 2021).

Credit

Syeda Rubaiya Nasrin, Christian Ganser, et al. Science Advances. October 13, 2021

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