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The Korea Advanced Institute of Science and Technology (KAIST)

Image 1

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Figure 1. The formula proposed by the FDA guidance for predicting drug-drug interactions (top) and the formula newly derived by the researchers (bottom). AUCR (the ratio of substrate area under the plasma concentration-time curve) represents the rate of change in drug concentration due to drug interactions. The research team more than doubled the accuracy of drug interaction prediction compared to the existing formula.

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Biomedical Mathematics Group, Institute for Basic Science (IBS)

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