DMAPO and Boc2O chemicals and a single reaction vessel (IMAGE)

Tohoku University

DMAPO and Boc2O chemicals and a single reaction vessel

Caption

Optimized reaction conditions for amide bond formation in nitrogen-containing heterocyclic compounds using carboxylic acid requires only 4-(N,N-dimethylamino)pyridine N-oxide (DMAPO) and di-tertbutyl dicarbonate (Boc2O) in a single reaction vessel.

Credit

Atsushi Umehara

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