A New Technique Creates Greater Fidelity in Bioprinting Functional Human Tissues (IMAGE)

University of California - San Diego

A New Technique Creates Greater Fidelity in Bioprinting Functional Human Tissues

Caption

One of the most promising types of 3D-bioprinting is called digital light processing (DLP) bioprinting. Within this branch of 3D-bioprinting, progress has been impeded by practical and technical impediments. It has proven difficult, for example, to print tissues with high cell densities and finely resolved structures. UC San Diego engineers published exciting advances that address this problem in the journal Science Advances published on Feb. 22, 2003. Using existing approaches, the more dense the presence of cells in bioink, which is a biocompatible polymer used in DLP-based 3D bioprinting, the more the light scatters, hindering printing resolution. The UC San Diego researchers reduced this light-scattering effect by tenfold, allowing them to print with high cell densities and high resolution thanks to the contrast agent iodixanol, a new ingredient in the bioink. Video b-roll is available at: https://www.youtube.com/watch?v=h-B_qLPOzCI Additional photos are also available.

Credit

UC San Diego Jacobs School of Engineering / David Baillot

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