Figure 2. DEtail-seq profiled meiotic DNA breaks. (IMAGE)
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A. Representative snapshots of Watson (blue) and Crick (red) DEtail-seq signals in WT 0h, WT 4h, dmc1Δ 4h, and spo11Δ 4h, and S1-seq and Spo11-oligo-seq signals in WT 4h. B. Metaplot of Watson or Crick DEtail-seq signals in two biological replicates of Sertoli cells or leptotene/zygotene stage cells on leptotene stage de novo H3K4me3 peaks. C. Metaplot of Watson or Crick DEtail-seq signals on enhancers overlapping without CTCF peaks (CTCF– enhancer), or with CTCF peaks (CTCF+ enhancer).
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