Figure 2 (IMAGE)
Caption
(A) POLQ is able to anneal two single-stranded DNA tails utilizing a short homology sequence and is able to bypass DNA damage. (B) A model of POLQ-mediated repair following high LET radiation. POLQ promotes synapsis formation of the two resected 3’-single-stranded DNA tails and efficiently bypasses DNA damage located on the tails.
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Institute for Basic Science
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