Fig. 3 (IMAGE)

Osaka University

Fig. 3

Caption

Tej interacts with Spn-E and Vas and has a role in processing piRNA precursors. In Drosophila germ cells, Spn-E localizes to the nuage in the perinuclear membrane region via the eSRS motif in Tej. In contrast, the Lotus domain of Tej facilitates Vas localization to the nuage. This complex is involved in the processing of piRNA precursors, and the IDR of Tej provides mobility to the Tej–Vas complex in the nuage, contributing to its role as a component of a non-membrane organelle.

Credit

2023, Toshie Kai, Tejas functions as a core component in nuage and precursor processing in Drosophila piRNA biogenesis, Journal of Cell Biology

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