News Release

Preterm birth might be predicted with high accuracy with new cheap, non-invasive test, based on cell-free DNA collected in standard early pregnancy testing

Peer-Reviewed Publication

PLOS

Preterm birth might be predicted with high accuracy with new cheap, non-invasive test, based on cell-free DNA collected in standard early pregnancy testing

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Schematic overview of predicting preterm birth using promoter profiling of plasma cfDNA.

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Credit: Guo Z, et al., 2025, PLOS Medicine, CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0/)

In your coverage, please use this URL to provide access to the freely available paper in PLOS Medicine: https://plos.io/3RuCJ9v

Article title: Genome-wide nucleosome footprints of plasma cfDNA predict preterm birth: A case-control study

Author countries: China, United Kingdom

Funding: This work was supported by project grants from the National Natural Science Foundation of China [81600404 to JT, 82270600 to JT, 81871177 to FY, 82271711 to XY, 82173001 to ZG]; Guangdong Basic and Applied Basic Research Foundation [2022A1515220204 to JT; 2024A1515012792 to ZG]; Guangzhou Key Laboratory of Molecular and Functional Imaging for Clinical Translation [201905010003 to JT]; The Research Foundation of Guangdong Provincial Reproductive Science Institute [QD202201 to JT]. No funders had any role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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