The Journal of Nuclear Medicine ahead-of-print tip sheet: April 18, 2025

Reston, VA (April 18, 2025)—New research has been published ahead-of-print by The Journal of Nuclear Medicine (JNM). JNM is published by the Society of Nuclear Medicine and Molecular Imaging, an international scientific and medical organization dedicated to advancing nuclear medicine, molecular imaging, and theranostics—precision medicine that allows diagnosis and treatment to be tailored to individual patients in order to achieve the best possible outcomes.

Summaries of the newly published research articles are provided below.

A New Way to See Triple-Negative Breast Cancer
Triple-negative breast cancer is tough to diagnose and treat due to its diverse nature. Scientists developed a novel imaging agent targeting a shared protein in these tumors. Tested in lab models, this agent successfully highlighted various tumor types using PET/CT scans, offering hope for better, more precise detection.

Improving Parkinsonism Diagnosis with a New Brain Scan
A new brain imaging technique using ¹⁸F-florzolotau shows promise in identifying complex brain diseases like progressive supranuclear palsy and corticobasal degeneration in real-world patients. By recognizing specific visual patterns in PET scans, doctors can better distinguish these disorders from others, offering a more accurate and practical tool for diagnosis.

Early PET Scans May Predict CAR T Therapy Success in Lymphoma
CAR T therapy helps many with aggressive lymphoma, but not all patients stay in remission. This study shows that PET scans taken one and three months after treatment—analyzing tumor activity and size—can help predict who is at higher risk of poor outcomes, potentially guiding earlier, more personalized care decisions.

Bigger Scanners, Smarter Spending: PET/CT Imaging Gets a Boost
A new study compares traditional PET/CT scanners with long–axial-field-of-view (LAFOV) systems and finds LAFOV scanners more cost-effective worldwide. They scan more patients, need fewer staff, and use less radiation—making them a smart investment not just for large hospitals but also for clinics in lower-income regions.

Visit the JNM website for the latest research, and follow our new Twitter and Facebook pages @JournalofNucMed or follow us on LinkedIn.

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Please visit the SNMMI Media Center for more information about molecular imaging and precision imaging. To schedule an interview with the researchers, please contact Rebecca Maxey at (703) 652-6772 or rmaxey@snmmi.org.

About JNM and the Society of Nuclear Medicine and Molecular Imaging

The Journal of Nuclear Medicine (JNM) is the world’s leading nuclear medicine, molecular imaging and theranostics journal, accessed 15 million times each year by practitioners around the globe, providing them with the information they need to advance this rapidly expanding field. Current and past issues of The Journal of Nuclear Medicine can be found online at http://jnm.snmjournals.org.

JNM is published by the Society of Nuclear Medicine and Molecular Imaging (SNMMI), an international scientific and medical organization dedicated to advancing nuclear medicine, molecular imaging, and theranostics—precision medicine that allows diagnosis and treatment to be tailored to individual patients in order to achieve the best possible outcomes. For more information, visit www.snmmi.org.